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AMLX
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Amylyx Pharmaceuticals, Inc.

AMLX · Healthcare · Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for ne…

Amylyx Pharmaceuticals, Inc. (AMLX), in the Healthcare sector, has 19 disclosed filings on Paydirt over the trailing twelve months from 6 corporate insiders: 1 purchase and 18 sales. Filers took a median of 2 days from execution to disclosure, and the most recent trade was executed Sep 10 and filed Sep 14. The most active filer was Joshua B Cohen with 5 filings.

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Filings, ttm
19
1 buy · 18 sells
Traders, ttm
6
6 insiders
Volume, ttmiDollar value disclosed in the window
$9.8M
estimated for Congress, as filed for insiders
Median delay
2d
execution to disclosure
Last traded
Sep 10
Filed Sep 14
ADViAverage daily dollar volume
$78.0M
market data
Share price · 12M
$32.41 (+143.5%)
$39.66$25.52$11.38Sep 22 2025Mar 23Sep 18

Adjusted for splits and dividends.

Volume by month
$3.7M$1.9M$0Oct 2024Apr 2025Oct 2025Apr 2026Aug 2025 · sells $246KOct 2025 · sells $1.3MDec 2025 · buys $101KJan 2026 · sells $3.7MFeb 2026 · sells $455KMar 2026 · sells $963KJul 2026 · sells $539KSep 2026 · sells $2.8M
Buys $101K Sells $10.0M

Estimated for Congress, as filed for insiders · by filing month · past 24 months

Who filed
JC Joshua B Cohen Co-Chief Executive Officer 5 filings JK Justin B. Klee Co-Chief Executive Officer 5 filings GM Gina Mazzariello Chief Legal Officer 4 filings JF James M Frates Chief Financial Officer 3 filings CB Camille L Bedrosian Chief Medical Officer 2 filings KF Karen Firestone Director 1 filing
Recent filings
Camille L BedrosianSALE Chief Medical Officer $256K
7,947 sh × $32.21
Exec Sep 10
Filed Sep 14 · 4:00 PM ET
James M FratesSALE Chief Financial Officer $315K
9,768 sh × $32.27
Exec Sep 10
Filed Sep 14 · 4:00 PM ET
Gina MazzarielloSALE Chief Legal Officer $309K
9,525 sh × $32.46
Exec Sep 10
Filed Sep 14 · 4:00 PM ET
Justin B. KleeSALE Co-Chief Executive Officer $933K
29,025 sh × $32.13
Exec Sep 10
Filed Sep 14 · 4:00 PM ET
Joshua B CohenSALE Co-Chief Executive Officer $950K
29,545 sh × $32.16
Exec Sep 10
Filed Sep 14 · 4:00 PM ET
Gina MazzarielloSALE Chief Legal Officer $539K
30,000 sh across 2 lots
Exec Jul 9
Filed Jul 13 · 4:00 PM ET
James M FratesSALE Chief Financial Officer $115K
7,909 sh × $14.52
Exec Mar 2
Filed Mar 4 · 5:30 PM ET
Joshua B CohenSALE Co-Chief Executive Officer $424K
29,282 sh × $14.48
Exec Mar 2
Filed Mar 4 · 5:30 PM ET
Justin B. KleeSALE Co-Chief Executive Officer $424K
29,282 sh × $14.47
Exec Mar 2
Filed Mar 4 · 5:30 PM ET
Justin B. KleeSALE Co-Chief Executive Officer $228K
15,500 sh × $14.69
Exec Feb 2
Filed Feb 4 · 5:30 PM ET
Joshua B CohenSALE Co-Chief Executive Officer $228K
15,500 sh × $14.68
Exec Feb 2
Filed Feb 4 · 5:30 PM ET
Justin B. KleeSALE Co-Chief Executive Officer $1.8M
136,193 sh × $13.58
Exec Jan 15
Filed Jan 20 · 5:30 PM ET
Joshua B CohenSALE Co-Chief Executive Officer $1.9M
136,193 sh × $13.59
Exec Jan 15
Filed Jan 20 · 5:30 PM ET
Karen FirestonePURCHASE Director $101K
8,100 sh × $12.45
Exec Dec 23 2025
Filed Dec 23 2025 · 8:48 PM ET
Camille L BedrosianSALE Chief Medical Officer $176K
12,039 sh × $14.58
Exec Sep 30 2025
Filed Oct 2 2025 · 5:30 PM ET
Joshua B CohenSALE Co-Chief Executive Officer $426K
29,733 sh × $14.34
Exec Sep 30 2025
Filed Oct 2 2025 · 5:30 PM ET
James M FratesSALE Chief Financial Officer $155K
10,558 sh × $14.65
Exec Sep 30 2025
Filed Oct 2 2025 · 5:30 PM ET
Gina MazzarielloSALE Chief Legal Officer $129K
8,828 sh × $14.58
Exec Sep 30 2025
Filed Oct 2 2025 · 5:30 PM ET
Justin B. KleeSALE Co-Chief Executive Officer $428K
29,775 sh × $14.37
Exec Sep 30 2025
Filed Oct 2 2025 · 5:30 PM ET
Gina MazzarielloSALE Chief Legal Officer $246K
30,000 sh across 2 lots
Exec Aug 12 2025
Filed Aug 14 2025 · 5:30 PM ET
James M FratesPURCHASE Chief Financial Officer
40,000 sh · price not plausible
Exec Sep 12 2024
Filed Sep 16 2024 · 5:30 PM ET
Karen FirestonePURCHASE Director
50,000 sh · price not plausible
Exec Sep 5 2024
Filed Sep 9 2024 · 5:30 PM ET