Orbimed Advisors Llc sold $22.9M of Sionna Therapeutics (SION)

Executed Apr 14, disclosed Apr 16, 2 days later.

Value, as filed

$22.9M

510,583 sh across 3 lots

Executed

Apr 14

the trade date, as filed

Disclosed

Apr 16

2 days after the trade

Return, 21 sessionsiFrom the disclosed entry session; derived

–

purchases only

Returns are measured on stock purchases only.

The filer

OL Orbimed Advisors Llc Director profile →

Orbimed Advisors Llc (Director) filed 18 Form 4 reports as a reporting entity in the trailing twelve months (10 purchases, 8 sales, 1 filed past the two-business-day deadline), most often in Sionna Therapeutics, Inc. (SION). Across 8 priced purchase filings, the average 21-session return was +11.7% from execution and +14.6% from disclosure (delay-adjusted; derived). The largest single filing was $38.9M of ELVN (858,646 sh across 3 lots, as filed), executed Jun 22.

The name

SION

Sionna Therapeutics, Inc. SION · Healthcare · 45 filings in 24 months ticker →

Healthcare · Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibros…

More Healthcare filings→ Insider filings, newest first→ View the original filing at www.sec.gov→

Other filings by Orbimed Advisors Llc in SION

SIONSALE Sionna Therapeutics, Inc. $3.9M
85,918 sh × $44.86
Exec Jul 7
Filed Jul 9 · 4:44 PM ET SIONSALE Sionna Therapeutics, Inc. $5.3M
115,844 sh × $45.50
Exec Jun 30
Filed Jul 2 · 4:42 PM ET SIONSALE Sionna Therapeutics, Inc. $13.4M
292,952 sh across 3 lots
Exec May 7
Filed May 11 · 5:30 PM ET SIONSALE Sionna Therapeutics, Inc. $2.5M
55,345 sh across 2 lots
Exec Apr 17
Filed Apr 21 · 5:30 PM ET SIONSALE Sionna Therapeutics, Inc. $4.7M
106,473 sh across 2 lots
Exec Nov 24 2025
Filed Nov 26 2025 · 5:30 PM ET