SYRE
Ticker
Spyre Therapeutics, Inc.
SYRE · Healthcare · Spyre Therapeutics, Inc., a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory…Spyre Therapeutics, Inc. (SYRE), in the Healthcare sector, has 29 disclosed filings on Paydirt over the trailing twelve months from 7 corporate insiders: 0 purchases and 29 sales. Filers took a median of 2 days from execution to disclosure, and the most recent trade was executed Oct 1 and filed Oct 3. The most active filer was Cameron Turtle with 11 filings. Data as of Nov 8 2026.
Add to watchlistFilings, ttm
29
0 buys · 29 sells
Traders, ttm
7
7 insiders
Volume, ttmiDollar value disclosed in the window
$441.0M
estimated for Congress, as filed for insiders
Median delay
2d
execution to disclosure
Last traded
Oct 1
Filed Oct 2
ADViAverage daily dollar volume
$134.1M
market data
Share price · 12M
$85.69 (+286.3%)
Adjusted for splits and dividends.
Volume by month
Buys $0
Sells $442.4M
Estimated for Congress, as filed for insiders · by filing month · past 24 months
Who filed · past 24 months
CTRecent filings
Heidy King-JonesSALE
See Remarks
$2.6M28,533 sh across 4 lots
Exec Oct 1
Filed Oct 2 · 9:30 PM ET Cameron TurtleSALE Chief Executive Officer $1.3M
14,300 sh across 4 lots
Exec Oct 1
Filed Oct 2 · 9:29 PM ET Scott L BurrowsSALE Chief Financial Officer $2.2M
24,171 sh across 4 lots
Exec Sep 30
Filed Oct 2 · 9:29 PM ET Heidy King-JonesSALE See Remarks $2.4M
27,599 sh across 3 lots
Exec Sep 1
Filed Sep 3 · 9:34 PM ET Scott L BurrowsSALE Chief Financial Officer $2.2M
24,632 sh across 3 lots
Exec Sep 1
Filed Sep 3 · 9:33 PM ET Cameron TurtleSALE Chief Executive Officer $1.3M
14,600 sh across 3 lots
Exec Sep 1
Filed Sep 3 · 9:33 PM ET Jeffrey W. AlbersSALE Director $2.4M
23,000 sh across 3 lots
Exec Aug 7
Filed Aug 10 · 9:31 PM ET Scott L BurrowsSALE Chief Financial Officer $707K
7,400 sh across 2 lots
Exec Aug 3
Filed Aug 5 · 9:32 PM ET Cameron TurtleSALE Chief Executive Officer $1.4M
14,184 sh across 3 lots
Exec Aug 3
Filed Aug 5 · 9:31 PM ET Scott L BurrowsSALE Chief Financial Officer $658K
7,500 sh across 2 lots
Exec Jul 1
Filed Jul 2 · 9:33 PM ET Sheldon SloanSALE Chief Medical Officer $731K
8,334 sh across 2 lots
Exec Jul 1
Filed Jul 2 · 9:33 PM ET Cameron TurtleSALE Chief Executive Officer $1.3M
14,410 sh across 2 lots
Exec Jul 1
Filed Jul 2 · 9:32 PM ET Scott L BurrowsSALE Chief Financial Officer $1.3M
15,000 sh across 2 lots
Exec Jun 25
Filed Jun 26 · 5:30 PM ET Michael Thomas HendersonSALE Director $2.0M
20,000 sh × $100.00
Exec Jun 22
Filed Jun 23 · 5:30 PM ET Fairmount Funds Management LLCSALE Director $399.7M
4,684,781 sh × $85.31
Exec Jun 23
Filed Jun 23 · 5:30 PM ET Scott L BurrowsSALE Chief Financial Officer $533K
7,500 sh across 3 lots
Exec Jun 1
Filed Jun 3 · 5:30 PM ET Cameron TurtleSALE Chief Executive Officer $1.1M
15,000 sh across 3 lots
Exec Jun 1
Filed Jun 3 · 5:30 PM ET Sheldon SloanSALE Chief Medical Officer $625K
8,333 sh × $75.00
Exec Jun 3
Filed Jun 3 · 5:30 PM ET Michael Thomas HendersonSALE Director $6.0M
80,000 sh across 4 lots
Exec May 8
Filed May 8 · 5:30 PM ET Cameron TurtleSALE Chief Executive Officer $976K
13,700 sh across 4 lots
Exec May 1
Filed May 1 · 5:30 PM ET Sheldon SloanSALE Chief Medical Officer $5.6M
77,933 sh across 6 lots
Exec May 1
Filed May 1 · 5:30 PM ET Scott L BurrowsSALE Chief Financial Officer $892K
12,500 sh × $71.37
Exec May 1
Filed May 1 · 5:30 PM ET Scott L BurrowsSALE Chief Financial Officer $305K
6,200 sh × $49.21
Exec Apr 1
Filed Apr 3 · 5:30 PM ET Sheldon SloanSALE Chief Medical Officer $398K
7,958 sh × $50.00
Exec Apr 1
Filed Apr 3 · 5:30 PM ET Cameron TurtleSALE Chief Executive Officer $740K
15,000 sh across 2 lots
Exec Apr 1
Filed Apr 3 · 5:30 PM ET