Paydirt
EL
Insider

EcoR1 Capital, LLC

Director

EcoR1 Capital, LLC (Director) filed 2 Form 4 reports as a reporting entity in the trailing twelve months (2 purchases, 0 sales), most often in ZYME. Across 2 priced purchase filings, the average 21-session return was +2.8% from execution and -5.0% from disclosure (delay-adjusted; derived). The largest single filing was $40.0M of AKTS (2,222,222 sh across 2 lots, as filed), executed Jan 12.

Add to watchlist
Return, ttmiAverage return per filing, trailing twelve months
+2.8%
avg across 2 priced filings
Delay-adjustediThe same average, entered at disclosure dates
-5.0%
same 2 filings, from disclosure
Filings, ttm
2
2 buys · 0 sells
Median delay
2d
execution → disclosure
Volume, ttmiDollar value disclosed in the trailing twelve months
$44.7M
shares × price, as filed
Last traded
May 7
Filed May 11

Median ADV $8.9M across their filed names

Impact on $10,000 · 12M
$8,773 (-12.3%)
S&P 500 $11,725 (+17.2%) · 29.5 pts behind
$11.8k$9.8k$7.9kSep 22 2025Mar 23Sep 21
EcoR1 Capital, LLC S&P 500

Compounded across filings from disclosure dates · past 12 months

Open performance
Volume by month
$50.8M$25.4M$0Oct 2024Apr 2025Oct 2025Apr 2026Nov 2024 · sells $8.4MDec 2024 · buys $19.4MJan 2025 · buys $13.6MMar 2025 · buys $5.7MApr 2025 · buys $2.9MMay 2025 · buys $39.3MMay 2025 · sells $50.8MJul 2025 · sells $6.7MJan 2026 · buys $40.0MMay 2026 · buys $4.7M
Buys $125.6M Sells $66.0M

Shares × price, as filed · by filing month · past 24 months

Sectors filed on
Healthcare 2 filings

Sector per market data · by filing · past 12 months

Most traded names
ZYME ZYME ZYME · 12 buys · 0 sells 12 filings ADAP ADAP ADAP · 0 buys · 1 sell 1 filing AKTS Aktis Oncology, Inc. AKTS · 1 buy · 0 sells 1 filing ANAB ANAB ANAB · 1 buy · 0 sells 1 filing ATRA Atara Biotherapeutics, Inc. ATRA · 1 buy · 0 sells 1 filing
Recent filings
ZYMEPURCHASE Zymeworks Inc. View filing → $1.9M
130,309 sh across 3 lots
Exec Dec 24 2024
Filed Dec 27 2024 · 5:30 PM ET
ZYMEPURCHASE Zymeworks Inc. View filing → $17.5M
1,254,808 sh across 3 lots
Exec Dec 19 2024
Filed Dec 26 2024 · 5:30 PM ET †
TNGXSALE Tango Therapeutics, Inc. View filing → $8.4M
2,700,000 sh across 3 lots
Exec Nov 6 2024
Filed Nov 8 2024 · 5:30 PM ET