OI
Insider
Opaleye Management Inc.
10% ownerOpaleye Management Inc. (10% owner) filed 36 Form 4 reports as a reporting entity in the trailing twelve months (22 purchases, 14 sales, 3 filed past the two-business-day deadline), most often in CDXS. Across 18 priced purchase filings, the average 21-session return was +19.2% from execution and +19.4% from disclosure (delay-adjusted; derived). The largest single filing was $7.8M of HROW (197,263 sh across 3 lots, as filed), executed Mar 3.
Add to watchlistReturn, ttmiAverage return per filing, trailing twelve months
+19.2%
avg across 18 priced filings
Delay-adjustediThe same average, entered at disclosure dates
+19.4%
same 18 filings, from disclosure
Filings, ttm
36
22 buys · 14 sells · 3 late
Median delay
2d
execution → disclosure
Volume, ttmiDollar value disclosed in the trailing twelve months
$39.4M
shares × price, as filed
Last traded
Sep 16
Filed Sep 16
Median ADV $2.8M across their filed names
Impact on $10,000 · 12M
$34,347 (+243.5%)
S&P 500 $11,723 (+17.2%) · 226.2 pts ahead
Opaleye Management Inc.
S&P 500
Compounded across filings from disclosure dates · past 12 months
Open performance→Volume by month
Buys $26.1M
Sells $25.8M
Shares × price, as filed · by filing month · past 24 months
Sectors filed on
Healthcare
28 filings
Not on file
8 filings
Sector per market data · by filing · past 12 months
Most traded names
CDXS
CDXS
CDXS · 17 buys · 5 sells
22 filings
SLGLRecent filings
SLGLPURCHASE
Sol-Gel Technologies Ltd.
View filing →
$123K2,173 sh × $56.57
Exec Jan 22
Filed Jan 23 · 5:42 PM ET HROWSALE Harrow, Inc. View filing → $1.1M
20,000 sh × $53.35
Exec Jan 6
Filed Jan 8 · 5:30 PM ET SLGLPURCHASE Sol-Gel Technologies Ltd. View filing → $100K
2,394 sh × $41.92
Exec Jan 2
Filed Jan 6 · 4:05 PM ET SLGLPURCHASE Sol-Gel Technologies Ltd. View filing → $2.8M
66,304 sh across 3 lots
Exec Dec 29 2025
Filed Dec 31 2025 · 5:45 PM ET