Opaleye Management Inc. sold $593K of Codexis (CDXS)

Executed Nov 28 2025, disclosed Dec 1 2025, 3 days later.

Value, as filed

$593K

350,000 sh across 2 lots

Executed

Nov 28 2025

the trade date, as filed

Disclosed

Dec 1 2025

3 days after the trade

Return, 21 sessionsiFrom the disclosed entry session; derived

–

purchases only

Returns are measured on stock purchases only.

The filer

OI Opaleye Management Inc. 10% owner profile →

Opaleye Management Inc. (10% owner) filed 36 Form 4 reports as a reporting entity in the trailing twelve months (22 purchases, 14 sales, 3 filed past the two-business-day deadline), most often in CDXS. Across 18 priced purchase filings, the average 21-session return was +19.2% from execution and +19.4% from disclosure (delay-adjusted; derived). The largest single filing was $7.8M of HROW (197,263 sh across 3 lots, as filed), executed Mar 3.

The name

CDXS CDXS CDXS · 22 filings in 24 months ticker → Insider filings, newest first→ View the original filing at www.sec.gov→

Other filings by Opaleye Management Inc. in CDXS

CDXSSALE CODEXIS, INC. $851K
498,318 sh across 3 lots
Exec Nov 26 2025
Filed Dec 15 2025 · 5:30 PM ET † CDXSSALE CODEXIS, INC. $323K
165,000 sh × $1.96
Exec Nov 12 2025
Filed Nov 14 2025 · 5:30 PM ET CDXSSALE CODEXIS, INC. $1.3M
740,000 sh across 2 lots
Exec Nov 10 2025
Filed Nov 12 2025 · 5:30 PM ET CDXSSALE CODEXIS, INC. $1.8M
1,036,682 sh across 3 lots
Exec Nov 7 2025
Filed Dec 15 2025 · 5:30 PM ET † CDXSPURCHASE CODEXIS, INC. $226K
84,220 sh × $2.68
Exec Jul 31 2025
Filed Aug 4 2025 · 4:38 PM ET CDXSPURCHASE CODEXIS, INC. $282K
100,000 sh × $2.82
Exec Jul 18 2025
Filed Jul 22 2025 · 4:05 PM ET CDXSPURCHASE CODEXIS, INC. $239K
100,000 sh × $2.39
Exec Jun 27 2025
Filed Jul 1 2025 · 5:30 PM ET CDXSPURCHASE CODEXIS, INC. $560K
250,000 sh across 3 lots
Exec Jun 12 2025
Filed Jun 16 2025 · 5:30 PM ET