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Baker Bros. Advisors Lp

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Baker Bros. Advisors Lp (Other) filed 5 Form 4 reports as a reporting entity in the trailing twelve months (4 purchases, 1 sale), most often in Celcuity Inc. (CELC). Across 4 priced purchase filings, the average 21-session return was +14.0% from execution and +7.3% from disclosure (delay-adjusted; derived). The largest single filing was $317.8M of CELC (3,100,000 sh across 2 lots, as filed), executed Jul 14.

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Return, ttmiAverage return per filing, trailing twelve months
+14.0%
avg across 4 priced filings
Delay-adjustediThe same average, entered at disclosure dates
+7.3%
same 4 filings, from disclosure
Filings, ttm
5
4 buys · 1 sells
Median delay
2d
execution → disclosure
Volume, ttmiDollar value disclosed in the trailing twelve months
$551.5M
shares × price, as filed
Last traded
Jul 14
Filed Jul 16

Median ADV $194.4M across their filed names

Impact on $10,000 · 12M
$11,612 (+16.1%)
S&P 500 $11,725 (+17.2%) · 1.1 pts behind
$13.7k$11.1k$8.6kSep 22 2025Mar 23Sep 21
Baker Bros. Advisors Lp S&P 500

Compounded across filings from disclosure dates · past 12 months

Open performance
Volume by month
$317.8M$158.9M$0Oct 2024Apr 2025Oct 2025Apr 2026Aug 2025 · buys $61.2MSep 2025 · buys $9.5MNov 2025 · buys $1.3MDec 2025 · buys $232.5MJul 2026 · sells $317.8M
Buys $304.6M Sells $317.8M

Shares × price, as filed · by filing month · past 24 months

Sectors filed on
Healthcare 4 filings Not on file 1 filing

Sector per market data · by filing · past 12 months

Most traded names
CELC Celcuity Inc. CELC · 1 buy · 1 sell 2 filings MDGL Madrigal Pharmaceuticals, Inc. MDGL · 2 buys · 0 sells 2 filings TRDA Entrada Therapeutics, Inc. TRDA · 2 buys · 0 sells 2 filings KOD KOD KOD · 1 buy · 0 sells 1 filing KYMR Kymera Therapeutics, Inc. KYMR · 1 buy · 0 sells 1 filing
Recent filings
CELCSALE Celcuity Inc. View filing → $317.8M
3,100,000 sh across 2 lots
Exec Jul 14
Filed Jul 16 · 5:42 PM ET
KODPURCHASE Kodiak Sciences Inc. View filing → $60.0M
2,608,696 sh across 2 lots
Exec Dec 18 2025
Filed Dec 19 2025 · 4:06 PM ET
KYMRPURCHASE Kymera Therapeutics, Inc. View filing → $172.5M
2,005,813 sh across 2 lots
Exec Dec 11 2025
Filed Dec 11 2025 · 4:19 PM ET
TRDAPURCHASE Entrada Therapeutics, Inc. View filing → $240K
26,468 sh across 2 lots
Exec Nov 20 2025
Filed Nov 24 2025 · 4:09 PM ET
TRDAPURCHASE Entrada Therapeutics, Inc. View filing → $1.0M
137,124 sh across 3 lots
Exec Nov 10 2025
Filed Nov 12 2025 · 5:34 PM ET
CELCPURCHASE Celcuity Inc. View filing → $9.5M
169,712 sh across 3 lots
Exec Sep 8 2025
Filed Sep 10 2025 · 4:06 PM ET
MDGLPURCHASE Madrigal Pharmaceuticals, Inc. View filing → $36.7M
96,519 sh across 22 lots
Exec Aug 18 2025
Filed Aug 20 2025 · 6:12 PM ET
MDGLPURCHASE Madrigal Pharmaceuticals, Inc. View filing → $24.5M
67,279 sh across 21 lots
Exec Aug 18 2025
Filed Aug 20 2025 · 6:09 PM ET