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Orbimed Advisors Llc

Director

Orbimed Advisors Llc (Director) filed 15 Form 4 reports as a reporting entity in the trailing twelve months (7 purchases, 8 sales, 1 filed past the two-business-day deadline), most often in Sionna Therapeutics, Inc. (SION). Across 7 priced purchase filings, the average 21-session return was +16.9% from execution and +18.9% from disclosure (delay-adjusted; derived). The largest single filing was $38.9M of ELVN (858,646 sh across 3 lots, as filed), executed Jun 22.

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Return, ttmiAverage return per filing, trailing twelve months
+16.9%
avg across 7 priced filings
Delay-adjustediThe same average, entered at disclosure dates
+18.9%
same 7 filings, from disclosure
Filings, ttm
15
7 buys · 8 sells · 1 late
Median delay
2d
execution → disclosure
Volume, ttmiDollar value disclosed in the trailing twelve months
$197.7M
shares × price, as filed
Last traded
Aug 10
Filed Aug 12

Median ADV $10.0M across their filed names

Impact on $10,000 · 12M
$16,673 (+66.7%)
S&P 500 $11,725 (+17.2%) · 49.5 pts ahead
$17.6k$12.2k$6.8kSep 22 2025Mar 23Sep 21
Orbimed Advisors Llc S&P 500

Compounded across filings from disclosure dates · past 12 months

Open performance
Volume by month
$51.6M$25.8M$0Oct 2024Apr 2025Oct 2025Apr 2026Oct 2024 · buys $14.0MMar 2025 · sells $270KMay 2025 · sells $2.7MJul 2025 · sells $4.9MSep 2025 · buys $5.5MSep 2025 · sells $900KOct 2025 · buys $5.0MNov 2025 · sells $4.7MApr 2026 · buys $13.5MApr 2026 · sells $25.4MMay 2026 · sells $13.4MJun 2026 · buys $15.0MJun 2026 · sells $51.6MJul 2026 · buys $15.0MJul 2026 · sells $9.1MAug 2026 · buys $44.9M
Buys $112.9M Sells $113.0M

Shares × price, as filed · by filing month · past 24 months

Sectors filed on
Healthcare 12 filings Not on file 3 filings

Sector per market data · by filing · past 12 months

Most traded names
SION Sionna Therapeutics, Inc. SION · 0 buys · 6 sells 6 filings ELVN Enliven Therapeutics, Inc. ELVN · 0 buys · 2 sells 2 filings ACET ACET ACET · 1 buy · 0 sells 1 filing BLSM BlossomHill Therapeutics, Inc. Common Stock BLSM · 1 buy · 0 sells 1 filing BRVE Braveheart Bio, Inc. BRVE · 1 buy · 0 sells 1 filing
Recent filings
SIONSALE Sionna Therapeutics, Inc. View filing → $13.4M
292,952 sh across 3 lots
Exec May 7
Filed May 11 · 5:30 PM ET
PRLDPURCHASE Prelude Therapeutics Inc View filing → $12.5M
2,815,315 sh across 2 lots
Exec Apr 21
Filed Apr 23 · 6:48 PM ET
SIONSALE Sionna Therapeutics, Inc. View filing → $2.5M
55,345 sh across 2 lots
Exec Apr 17
Filed Apr 21 · 5:30 PM ET
TRAWPURCHASE Traws Pharma, Inc. View filing → $998K
597,729 sh × $1.67
Exec Apr 16
Filed Apr 28 · 9:41 PM ET †
SIONSALE Sionna Therapeutics, Inc. View filing → $22.9M
510,583 sh across 3 lots
Exec Apr 14
Filed Apr 16 · 5:30 PM ET
SIONSALE Sionna Therapeutics, Inc. View filing → $4.7M
106,473 sh across 2 lots
Exec Nov 24 2025
Filed Nov 26 2025 · 5:30 PM ET
ACETPURCHASE Adicet Bio, Inc. View filing → $5.0M
5,000,000 sh across 2 lots
Exec Oct 8 2025
Filed Oct 10 2025 · 8:06 PM ET
PMVPSALE PMV Pharmaceuticals, Inc. View filing → $900K
500,000 sh × $1.80
Exec Sep 10 2025
Filed Sep 12 2025 · 5:30 PM ET
More filings →